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Jan 24, 2020
The genes and proteins that regulate circadian rhythms may not work properly in the lungs of those with idiopathic pulmonary fibrosis, a new research study suggests. Supporting the link between circadian rhythms and pulmonary fibrosis, the study also found that people who regularly sleep less than 4 hours or 11 or more hours per day are more likely to have the disease.
Nov 19, 2019
Animal models for IPF work to show how pulmonary fibrosis impacts the lungs, but not what regulates changes at the genetic level to drive IPF progression in humans. A new model for investigating human IPF aims at understanding the gene expression changes and molecular regulators that characterize the progression of IPF from histologically normal regions into end-stage disease.